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Gene Editing QC

Writing the Future of Gene Editing QC

Genome editing tools like transcription activator-like effector nucleases (TALENs) and zinc finger nucleases (ZFNs) revolutionized biomedical research. However, since the early 2010’s, no gene editing tool has been as powerful as CRISPR-Cas9.

The potential for therapeutic applications of gene editing cannot be understated, but further research is needed to ensure the intended edits are precisely implemented.

Creating proper QC methods are critical to this effort, and transposase-based approaches, with solutions such as seqWell’s Tagify UMI reagents, offer promise. Incorporating Tagify UMIs in conjunction with methods like UDiTaS™, can help researchers create QC benchmarks that will ultimately promote the development of safer and more effective gene editing.

Comprehensive QC with Tagify and ExpressPlex™

Leverage the combined power of Tagify and ExpressPlex™ Library Prep Kit for thorough gene editing quality control.

Precision Downstream QC with Tagify

Tagify, incorporating UMIs, quantifies gene editing efficiency and fidelity at the on-target molecular level, ensuring accurate assessment post-editing.

Verified Upstream QC with ExpressPlex™

Utilize the ExpressPlex™ Library Prep Kit as an innovative upstream QC method, verifying DNA sequence integrity before gene editing, creating a reliable QC sandwich for streamlined workflows and reproducible results.