Entries by Harshita Sharma

Knock-in Immortalized Cells

PRODUCTS

Knock-in Immortalized Cells

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Get CRISPR-Engineered Cell Lines Faster and More Efficiently.

EditCo’s Knock-in Immortalized Cells provide a fast and efficient way to integrate engineered cells into your research, using automated transfection optimization and RNP-based delivery to ensure high editing success with minimal off-target effects.

By eliminating the delays and challenges of DIY CRISPR projects, our cost-effective solution enables you to model more genes and variants across multiple cell lines, accelerating your path to discovery without overspending.

Tag and Quantify Your Protein:

Easily purify and measure your target protein with
precise tagging.

Create a Disease Model:

Modify genes to introduce or correct mutations for studying disease phenotypes.

Analyze Gene Regulation:

Develop reporter cell lines with promoter tags to monitor
gene activity.

Uncover Protein Interactions:

Use affinity tags to map protein-protein interactions and identify key partners.

Cost-Effective CRISPR Knock-in Cell Pools – Flexible & Efficient

EditCo’s Knock-in Immortalized Cell Pools provide a high-throughput, budget-friendly solution for introducing precise edits while maintaining a mixed population of edited and unedited cells.

  • – Optimized transfection for high-efficiency knock-ins
  • – Supports SNVs, tags, and large insertions with advanced HDR strategies
  • – Flexible clonal isolation—manage it yourself or opt for our Knock-in Clones
  • – Comprehensive QC & sequencing reports for reliable validation

Precision-Verified CRISPR Knock-in Clones – Ready for Your Research

EditCo’s Knock-in Immortalized Cell Clones provide a sequence-verified, clonal population for precise, high-quality knock-ins. Whether modifying SNVs, tagging proteins, or inserting large sequences, our automated isolation process ensures you receive a single-cell-derived clone with your desired edit.

  • – Guaranteed precision with fully validated knock-ins
  • – Endogenous tagging & SNV editing for functional studies
  • – Streamlined delivery with complete QC & sequencing reports
  • – Customizable options including additional clones & intermediate pools

Skip the complexity—get ready-to-use, precision-edited clones with EditCo!

Ready to Order?

Our team can help you in placing the order. Click below to get a quote and fast ordering.

Immortalized Cells Portfolio

Let’s Find You an Application That Helps
Your Research

Get a call from your local Decode Science representative to help you find the best fit genomics products for you.







    Or give us a call at:

    1300 581 991

    Knockout Immortalized Cells

    PRODUCTS

    Knockout Immortalized Cells

    Knock-in-Immortalized-Cell-Lines.webp

    Reliable, Reproducible CRISPR Editing for Breakthrough Discoveries

    Spend Less Time on Editing, More on Innovation: EditCo’s advanced automation eliminates time-consuming steps, allowing you to focus on impactful research.

    Superior Performance & Scalability: Our CRISPR platform delivers high knockout efficiencies, ensuring consistent, reproducible results across experiments.

    Characterize Genes Associated with Neurodegenerative Disease:

    Develop immortalized cell line models to uncover and characterize genes involved in Parkinson’s Disease.

    Investigate a Protein’s Mechanism of Action:

    Accelerate your data generation with high-quality reagents that avoid high off-target issues to quickly and confidently confirm protein function.

    Expedite Drug Discovery
    Research:

    Validate a new drug lead without having to invest time learning or optimizing CRISPR.

    Thoroughly Confirm Your Phenotype in Multiple Models in Parallel:

    Generate data in time for your next board meeting or publication by running assays in parallel to identify your targets.

    XDel Knockout Cell Pools & Clones

    XDel is an advanced CRISPR knockout tool that eliminates uncertainty in gene editing. Using a groundbreaking guide RNA design approach, it provides highly effective, reliable, and repeatable gene knockouts, enabling researchers to speed up their breakthroughs with assurance.

    • – Higher Efficiency & Consistency: XDel technology ensures superior on-target knockout rates with minimal variability.
    • – Reduced Off-Target Effects: Achieve precise edits with lower unintended mutations compared to single-guide methods.
    • – Validated & Scalable: Persistent protein depletion enables direct use in functional assays, drug discovery, and disease modeling.

    CRISPR Knockout Cell Pools & Clones

    Accelerate your research with high-efficiency CRISPR Knockout Cell Pools & Clones from EditCo. Our cell pools provide a mix of edited and unedited cells for immediate assays, while clonal lines ensure precise gene knockouts with sequence-verified accuracy.

    • – 50%+ knockout efficiency in cell pools
    • – Up to 95% protein knockout for functional validation
    • – Single, double, or triple knockouts available
    • – Comprehensive QC & sequencing reports included

    Knockout Cell Libraries – High-Throughput CRISPR Screening Made Easy

    EditCo’s Knockout Cell Libraries enable high-efficiency CRISPR screening with over 90% editing success in a ready-to-use 96-well arrayed format. Designed for functional assays and drug target discovery, our libraries eliminate transfection challenges and infrastructure barriers.

    • Multi-guide CRISPR design for precise knockouts
    • High-throughput screening with scalable workflows
    • – Comprehensive QC & sequencing reports included
    • – Compatible with diverse assays for discovery & validation

    Ready to Order?

    Our team can help you in placing the order. Click below to get a quote and fast ordering.

    Immortalized Cells Portfolio

    Let’s Find You an Application That Helps
    Your Research

    Get a call from your local Decode Science representative to help you find the best fit genomics products for you.







      Or give us a call at:

      1300 581 991

      Knockout T-cells

      PRODUCTS

      Knockout CD8+ & CD4+ T Cells

      Knockout-Tcells.webp

      Advanced CRISPR Knock-Ins for iPSC Research

      EditCo delivers efficient gene editing with guaranteed >80% efficiency in human primary cells, achieving >90% in many cases, using a smart multi-guide design and a 7-day protocol for results in 2 weeks or faster. Their Primary Cell KO Pools produce functionally consistent cell populations, ideal for drug discovery or biological modeling, while maintaining high viability and functionality. Researchers can use EditCo-supplied cells or their own CD8+/CD4+ T cells, ensuring flexibility and reliability. By minimizing failed experiments and false negatives, EditCo saves time and resources, offering 1M-cell EC Pools for high-quality, rapid, and dependable gene editing.

      Focus on your experiment while they handle CRISPR

      Their KO Primary T-cells ensure >80% editing efficiency, available with EditCo-supplied cells or your own experimental/clinical samples.

      Choose your starting point

      Options include EditCo-supplied cells or customer-provided samples, with edits available for single knockouts using multi-guide synthetic sgRNA.

      Transparent and detailed results

      Receive regular updates, 2 vials of edited cell pools (>1M cells/vial), control-transfected pools, gRNA sequences, NGS primers, sequencing reports, and a detailed QC analysis.

      Reliable and validated outcomes

      Each order includes a QC report with mycoplasma testing, passage number, and NGS analysis to ensure high-quality, functional edited cells.

      Image: High editing efficiency across multiple donors.

      Image: EditCo KO CD8+ T cell pools can be thawed and expanded for weeks, with or without TCR stimulation.

      Next-Level Edited CD8+ T Cells – Powerful, Stable, and Ready for Action

      Take your research further with precision-engineered CD8+ T cells that combine high editing efficiency, long-term stability, and exceptional functionality. Designed to maintain their knockout integrity, expand effortlessly post-thaw, and deliver strong antigen-specific responses, these cells are built for performance. Whether you’re exploring immune responses or advancing cell therapy, these edited T cell pools provide the reliability and power you need.

       

      🔬 Unmatched Editing Precision – Achieve over 90% knockout efficiency across multiple donors, maintaining stability before and after cryopreservation.

      🧬 Thrives & Expands with Ease – These cells stay healthy and proliferate for weeks, with or without stimulation, ensuring flexibility in your experiments.

      Optimized for Real-World Function – A single round of activation preserves normal function, preventing overstimulation and exhaustion.

      🎯 Potent, Targeted Cytotoxicity – Strong antigen-specific activation, with robust CD107a expression, ensures effective tumor-killing potential.

       

      Power up your research with CD8+ T cells engineered to perform when it matters most.

      CD4+ T Cells - Stability and Functionality Post-Editing

      The editing of CD4+ T cells has shown high efficiency and stability, with a robust ability to maintain functionality after the editing process. The efficiency of the CD4+ T cell editing was determined through ICE analysis, with results demonstrating high editing efficacy across multiple loci while ensuring cell viability during the freezing stage. Post-editing, the cells can be thawed and expanded without loss of functionality or editing efficiency. Cytokine production in edited T cells, including IFNg, IL2, and TNFa, indicates that the editing process does not negatively impact the cells’ ability to produce essential cytokines upon stimulation. These edited pools also show high viability, making them suitable for further downstream assays.

      • – High editing efficiency of CD4+ T cells determined by ICE analysis.
      • – No reduction in cell viability after freezing, as indicated by flow cytometry
      • – Successful expansion and thawing of edited cells without affecting functionality
      • – Edited cells exhibit high levels of cytokine production (IFNg, IL2, TNFa) post-stimulation 
      • – High viability and expansion potential, with >90% viability after 14 days in culture 
      • – Statistical analysis shows significant cytokine differences between edited and mock cells 

      Image: Editing Efficiency and Viability for CD4+ T cell pools.

      Image: Editing Efficiency leads to protein depletion as shown by flow cytometry

      Image: CD4+ pool stability after thaw.

      Ready to Order?

      Our team can help you in placing the order. Click below to get a quote and fast ordering.

      Let’s Find You an Application That Helps
      Your Research

      Get a call from your local Decode Science representative to help you find the best fit genomics products for you.







        Or give us a call at:

        1300 581 991

        Gene Knockout Kits

        PRODUCTS

        Gene Knockout Kits

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        EditCo Gene Knockout Kits: Reliable and Efficient CRISPR Solutions

        EditCo’s Gene Knockout Kit offers a simplified, highly efficient solution for generating human and mouse protein-coding gene knockouts. Unlike traditional CRISPR methods, which rely on a single guide RNA (gRNA) to create random indels, EditCo’s multi-guide approach ensures consistent and precise gene disruption. This method generates fragment deletions at the targeted loci, providing a more reliable and predictable knockout, ultimately enhancing experimental success. With fast delivery times (kits arrive in just 5 days), users can avoid the trial and error of guide screening and proceed quickly with their experiments. The process is streamlined further with an easy online ordering portal, which includes the option to purchase controls, SpCas9 nuclease, and Transfection Optimization kits to complement your knockout experiment. This solution guarantees high knockout efficiency, making gene editing faster and more reliable than ever before.

        Human and Mouse Knockouts

        Guaranteed for human and mouse genes (excluding non-essential genes), ensuring high knockout efficiency.

        Multi-Guide sgRNA

        Chemically modified sgRNA resists degradation and prevents immune responses for reliable gene editing.

        Complete CRISPR Solution

        Optional add-ons like the Transfection Optimization Kit, SpCas9 nuclease, and controls for a comprehensive experiment.

        Kit Contents

        Includes multiguide sgRNA, SpCas9 EZ Scaffold, buffers, water, and quality control documents for PCR and sequencing.

        Guaranteed Knockouts with Multi-Guide CRISPR

        EditCo’s Gene Knockout Kit uses a multi-guide gRNA approach to ensure reliable and efficient gene disruption. This method targets a single exon with three spatially coordinated gRNAs, creating multiple double-strand breaks and resulting in large fragment deletions. Compared to single-guide CRISPR, our multi-guide strategy significantly increases knockout efficiency, with over 75% large deletions and a 29.2% improvement in knockout success.

        • – High Knockout Efficiency: Multi-guide format provides up to 89.9% knockout success across 32 genetic targets.
        • – Reduced Off-Target Effects: Less occurrence of off-target edits compared to single-guide methods.
        • – Consistent Results: Fragment deletions lead to sustained protein depletion over time, confirmed through Western blot analysis.
        • – Reliable Gene Editing: Achieve complete knockout in just 7 days post-transfection.

        Image: Better knockout efficiency was found across 32 genetic targets assessed.

        Image: EditCo’s Gene Knockout Kit was designed to increase the efficacy of CRISPR-mediated knockouts.

        Image: Multi-guide gRNA for each target resulted in >75% large deletion outcomes.

        Image: Editing of three genes (CDK9, CINP, COASY) in HEK293 cells (transfected via nucleofection) using the multi-guide approach resulted in high knockout efficiencies, as indicated by Knockout (KO) Scores

        Ready to Order?

        Our team can help you in placing the order. Click below to get a quote and fast ordering.

        CRISPR Reagents Portfolio

        Let’s Find You an Application That Helps
        Your Research

        Get a call from your local Decode Science representative to help you find the best fit genomics products for you.







          Or give us a call at:

          1300 581 991

          Arrayed gRNA Libraries

          PRODUCTS

          Arrayed gRNA Libraries

          Arrayed-gRNA-Libraries.webp

          Smarter, Faster, and More Efficient CRISPR Screening

          Achieve unparalleled knockout efficiency with EditCo’s multi-guide CRISPR design. Our Arrayed CRISPR gRNA Libraries eliminate the inefficiencies of traditional loss-of-function screens, offering a reliable and ready-to-transfect solution. With up to three spatially coordinated sgRNAs per gene, our approach ensures higher knockout success, reduces false negatives, and eliminates the need for complex NGS data analysis. Designed for both human and mouse genes, our libraries provide fast delivery, robust quality control, and seamless Sanger sequencing analysis—so you can focus on results, not troubleshooting.

          Whole Genome CRISPR Libraries for Comprehensive Gene Editing

          EditCo’s Whole Human and Whole Mouse Genome Libraries provide unmatched gene coverage with our multi-guide design, ensuring high editing efficiency across 20,000+ gene targets. Designed for seamless transfection, these libraries reduce false negatives and eliminate time-consuming preparation, making large-scale CRISPR screening easier than ever.

          • – Comprehensive Coverage: Target the entire human or mouse genome with high knockout efficiency.
          • – Ready-to-Use Libraries: Pre-plated and transfection-ready, minimizing preparation time.
          • – Enhanced Stability: Chemically modified sgRNAs resist degradation and prevent immune responses.
          • – Flexible Formats: Available in 96- or 384-well plates with multi-guide sgRNAs for reliable gene disruption.

          Accelerate Target Discovery with Pathway Libraries

          EditCo’s 30+ Pathway Libraries, including druggable targets, GPCRs, kinases, and immuno-oncology genes, provide a powerful tool for target identification studies. Designed with our multi-guide CRISPR strategy, these libraries ensure high knockout efficiency and fewer false negatives. Select libraries ship in as little as one week, helping you start your screen faster.

          • – Diverse Pathway Coverage: Includes key gene sets for drug discovery and functional studies.
          • – Fast Shipping: Select libraries ready to ship within a week.
          • – High-Efficiency Knockouts: Multi-guide sgRNAs deliver precise, predictable gene disruption.
          • – Ready-to-Use Format: Available in 96- or 384-well plates with modified sgRNAs for stability.

          Available Gene Pathways

          Optimal Knockout Efficiency for High-Throughput Screening

           

          XDel technology delivers precise, high-efficiency knockouts by using a multi-guide RNA strategy that ensures consistent and reliable gene editing. Unlike traditional single-guide methods, XDel induces fragment deletions in early exons, maximizing on-target accuracy while minimizing variability and off-target effects.

          • Superior editing efficiency – Multi-guide design achieves higher and more consistent knockouts
          • Reduced off-target effects – XDel minimizes unintended edits compared to single-guide methods
          • Sustained knockout effects – Gene edits remain stable across multiple cell passages
          • High viability & protein depletion – Maintains cell health while ensuring effective functional knockouts

          Achieve robust genotype and phenotype screening with XDel’s optimized CRISPR knockout technology.

          Image: XDel multiple gRNA creates fragment deletions

          Image: XDel design includes up to 3 modified sgRNAs (grey bars) that target a single gene of interest

          Ready to Order?

          Our team can help you in placing the order. Click below to get a quote and fast ordering.

          CRISPR Reagents Portfolio

          Let’s Find You an Application That Helps
          Your Research

          Get a call from your local Decode Science representative to help you find the best fit genomics products for you.







            Or give us a call at:

            1300 581 991

            SR-X™ Biomarker Detection System

            PRODUCTS

            SR-X™ Biomarker Detection System

            THE SR-X™ BIOMARKER DETECTION SYSTEM

            The SR-X Ultra-Sensitive Biomarker Detection System leverages advanced Simoa® bead technology to provide researchers with a compact, cost-effective solution for ultra-sensitive biomarker detection. Designed for multiplexing, the SR-X can detect up to four analytes per well with minimal sample volume, optimizing both productivity and sample preservation. A comprehensive range of Simoa assay kits is available, delivering significantly enhanced sensitivity compared to traditional immunoassay methods. This ensures precise detection of biomarkers at both normal and acute levels across various sample types.

            Ultra-sensitive Simoa® Bead Technology

            Dectect multiplex analytes without compromising sensitivity or specificity

            Semi-Automated

            Simple 2-step or 3-step workflow with minimal user intervention

            Convenient

            Compact instrument with built-in touchscreen control and comprehensive data analysis tools

            Flexible

            Simple custom assay development for both protein and circulating nucleic acid detection

            Low-maintenance

            No daily or monthly user maintenance

            Multiplex Measurement of Low-Abundance Circulating Proteins

            The SR-X™ system enables multiplex detection of neurodegeneration biomarkers using the Simoa® bead-based assay. Healthy donor sample readings are presented alongside the lower limit of quantification (LLOQ), indicated by dashed lines, for each assay in its validated matrix.

            Ready to Order?

            Our team can help you in placing the order. Click below to get a quote and fast ordering.

            Quanterix Portfolio

            Let’s Find You an Application That Helps
            Your Research

            Get a call from your local Decode Science representative to help you find the best fit genomics products for you.







              Or give us a call at:

              1300 581 991

              Integrated online ordering portal between Twist Bioscience & Decode Science

              Integrated online ordering portal between Twist Bioscience & Decode Science!

              To streamline the ordering process for your Twist Gene Fragments, Clonal Genes, Oligo Pools, IgG Antibodies and Custom Vector Onboarding, Twist Bioscience has an integrated portal connecting your Twist Bioscience eCommerce account and Decode Science (channel partner for Twist Bioscience in Australia and New Zealand).

              All you need to do is: 

              Open your Twist eCommerce account www.twistbioscience.com, sign in and select what Twist can build for you: 

               

              Enter your own Project Name (Twist recommend giving meaningful names to projects, if you don’t assign one, Twist will use a default name. You can always change it later) 

              Select start a new project

              Upload your sequences, and follow the prompts through on each screen for your selected project for any of Twist’s synthesis services (NGS ordering not currently online yet)

              Navigate through each page, each product has different options etc*

               

              *If you are ordering genes and need to codon optimise your sequences, please select the gene to optimise and then click on “Codon Optimization” button on the top right of the next screen.

              The platform will then navigate you through the various steps involved. If you have difficulties please  contact your Decode team member and they can set up a virtual session to guide you.

              Twist also now have a bulk codon optimisation tool available – Codon Optimization Tool | Twist Bioscience

              Once you have completed all the details for your project follow the pages through to:

              Request quote – this will be provided directly from Decode Science in AUD and include any discount structure, promotional offers etc.



              You will receive email notification that Decode Science has received your quotation request and provided a project number Q-xxxxxx, which can be used to keep track of your orders.


              Decode Science will email you a quote within 24 hours.  If you would like to proceed with the purchase, please request a PO be generated for Decode Science and email through to support@decodescience.co.nz.  Credit card payment is also accepted


              Decode and Twist will take care of everything else, and you will receive your Twist DNA order delivered to your lab.

               – Keep track of your orders in your online account

               – Be notified when your order has been despatched to Decode Science


              If you have any enquiries, please do not hesitate to contact sales@decodescience.co.nz

              Smash the limits of single cell sequencing with Parse

              Smash the limits of single cell sequencing.

              Join us to learn about Parse’s single cell whole transcriptome technology and recently
              launched Evercode V3 Kits. More cells, more samples, more clarity.

              Combinatorial barcoding technology strips away the limitations and frustrations of yesterday’s single cell approach. It ditches the specialized instrument, freeing you to pursue unprecedented discoveries. Unleash the potential of single cell. Decode Science and Parse Biosciences invite you to a seminar discussing the advances in fixation-based single cell transcriptomics including our V3 chemistry, TCR/BCR kits, CRISPR Detect and Gene Capture.

               

              MEET THE SPEAKER

              John received his PhD at Duke University, where he studied cis-regulatory element activation during limb regeneration. He then spent a few years as a postdoc at the University of California, Merced where he studied early organ formation using single-cell genetic and epigenetic approaches. As a Field Application Scientist at Parse Biosciences, John assists scientists with their single-cell genomics experiments, from experimental design, sample preparation, single-cell library workflows, data analysis, and more.

              John’s favorite model organism are zebrafish, both embryos and adults. In his free time John enjoys eating spicy food, and dabbles in growing his own hot chili pepper plants.

              Auckland

              SEMINAR 1

              Date: 8th May 2024

              Time: 10am – 11am

              Location: University of Auckland FMHS Room 503-126

              SEMINAR 2

              Date: 8th May 2024

              Time: 1:30pm – 2.30pm 

              Location: University of Auckland Old Government House, VC Suite


              Dunedin

              Date: 6th May 2024

              Seminar 1: 10:30 AM : University of Otago Room 3.27 Dept of Biochemistry

              Seminar 2: 12 PM: University of Otago Barnett Lecture Theatre


              Wellington

              Date: 7th May 2024

              Seminar 1: 10:30 AM : Seminar Room, Malaghan Institute


              Brisbane

              Date: 10th May 2024

              Seminar 1: 10-11AM – Queensland Institute of Medical Research
              Seminar 2: 2PM – 3PM – Translational Research Institute Room 2003


              Sydney

              SEMINAR 1

              Date: 13th May 2024

              Time: 10 – 11am

              Location: Mackenzie Room, Charles Perkins Centre, University of Sydney.

              SEMINAR 2

              Date: 13th May 2024

              Time: 1 – 2pm

              Location: Level 5 Conference Room, Victor Chang Cardiac Research Institute.


              Melbourne

              Date: 14th May 2024

              Seminar: 3:00 PM – 4:00 PM – WEHI Davis Auditorium, Melbourne


              Canberra

              Date: 15th May 2024

              Time: 12:30 PM – 1:30 PM

              Location: Australian National University, John Curtin School of Medical Research, Finkel Theatre


              Perth

              SEMINAR 1

              Date: 17th May 2024

              Time: 10-11AM

              Location: Harry Perkins Research Institute in the McCusker Auditorium

              SEMINAR 2

              Date: 17th May 2024

              Time: 2PM – 3PM

              Location: 360.3.030, Boola Katitjin in Murdoch University

              Evercode TCR Mega

              PRODUCTS

              Evercode TCR Mega

              1M CELLS

              96 SAMPLES

              Unlock scalable immune profiling capabilities with Evercode™ TCR Mega, empowering you to analyze up to 1 million cells at a time. In the intricate landscape of immunity, comprehensive data is key. With Evercode™ TCR Mega, you can achieve unparalleled resolution in studying TCR clonotype diversity and T-cell states.

              Benefit from the expansive scale of Evercode™ TCR Mega, which offers a host of advantages alongside the wealth of information provided by WT profiles. Whether you’re exploring immune responses, investigating cellular dynamics, or delving into immunotherapy research, Evercode™ TCR Mega equips you with the tools to navigate the complexities of the immune system with confidence and precision.

              EXPONENTIALLY
              SCALABLE

              Evercode's combinatorial barcoding
              enables you to dramatically
              scale up the cells and samples per experiment.

              NO INSTRUMENT
              REQUIRED

              If you have a centrifuge,
              thermal cycler,
              and some pipettes,
              you’re ready to go.

              UNMATCHED DATA QUALITY

              Better detect lowly expressed
              genes and avoid ambient RNA common
              in droplet-based
              single cell sequencing.

              WORKS WITH FIXED CELLS AND NUCLEI

              Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.

              Up to 1 million cells in a single experiment

              Experience the power of scale with Evercode. Conduct experiments with up to 1 million cells in a single run, unlocking the immense diversity within the immune repertoire like never before. With Evercode, identify an extensive array of TCR clonotypes, providing unparalleled insights into immune function and response.

              Not only can Evercode detect clonotypes, but it also offers the capability to map them to T cell subtype clusters. By analyzing gene expression profiles from nearly 1 million T cells isolated from PBMCs, Evercode enables the classification of cells into distinct T cell subtypes. This comprehensive approach ensures a deeper understanding of immune dynamics and facilitates more nuanced analysis of immune responses.

              High TCR detection in activated and primary T cells

              Experience outstanding TCR detection in both activated and primary T cells with our cutting-edge profiling techniques. In our investigation, T cells derived from peripheral blood mononuclear cells (PBMCs) underwent two distinct conditions: direct profiling (Primary) and activation through culture for 3 days with CD3/CD28 beads and IL-2 (Activated).

              Our results demonstrate robust TCR detection in both experimental conditions, highlighting the versatility and reliability of our methodology across diverse T cell states. Whether profiling primary T cells or their activated counterparts, our approach ensures accurate and comprehensive characterization of the TCR repertoire, providing invaluable insights into immune responses and cellular dynamics.

              Trust in our advanced profiling techniques to deliver precise and high-fidelity data, enabling a deeper understanding of T cell biology and immunological processes. With our innovative methodologies, delve into the complexities of the immune system with confidence and clarity, paving the way for transformative discoveries in immunology.

              Comprehensive immune repertoire detection

              Immerse yourself in unparalleled detection of the immune repertoire with the Evercode™ TCR kit, meticulously crafted to offer the most comprehensive profile attainable. In a groundbreaking study spanning 8 donors, our kit revealed the identification of nearly 500,000 unique beta chain clonotypes.

              Notably, the majority of these clonotypes were deemed rare, emphasizing the remarkable sensitivity and depth of our detection capabilities. With the Evercode™ TCR kit at your disposal, you gain the ability to unveil the complete spectrum of immune diversity, from commonplace to exceptionally rare clonotypes. This empowers you to delve into the intricacies of immune responses with unparalleled precision and breadth, opening new avenues for exploration and discovery in immunology.

              tcr parse workflow

              Ready to Order?

              Our team can help you in placing the order. Click below to get a quote and fast ordering.

              Let’s Find You an Application That Helps
              Your Research

              Get a call from your local Decode Science representative to help you find the best fit genomics products for you.







                Or give us a call at:

                1300 581 991

                Evercode TCR

                PRODUCTS

                Evercode TCR

                10K CELLS

                12 SAMPLES

                Explore the depths of the immune repertoire with our cutting-edge solution: single-cell TCR profiling combined with whole transcriptome analysis—no additional instrumentation required.

                With our state-of-the-art technology, you can detect TCRs with remarkable sensitivity while simultaneously capturing transcriptome-wide gene expression, including essential T-cell subtype markers. Delve into the intricate cellular landscape and unlock unprecedented insights by examining paired alpha and beta sequences within individual cells.

                This revolutionary approach empowers you to unravel the complex interplay between TCR diversity and gene expression profiles at the single-cell level, providing a holistic understanding of immune responses and cellular heterogeneity. Bid farewell to the constraints of conventional methods and embark on a transformative journey in immunogenomics research with our integrated solution.

                EXPONENTIALLY
                SCALABLE

                Evercode's combinatorial barcoding
                enables you to dramatically
                scale up the cells and samples per experiment.

                NO INSTRUMENT
                REQUIRED

                If you have a centrifuge,
                thermal cycler,
                and some pipettes,
                you’re ready to go.

                UNMATCHED DATA QUALITY

                Better detect lowly expressed
                genes and avoid ambient RNA common
                in droplet-based
                single cell sequencing.

                WORKS WITH FIXED CELLS AND NUCLEI

                Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.

                High TCR detection in activated and primary T cells

                Witness exceptional TCR detection in both activated and primary T cells through our state-of-the-art profiling techniques. In our investigation, T cells sourced from peripheral blood mononuclear cells (PBMCs) underwent two distinct conditions: direct profiling (Primary) and activation via culture for 3 days with CD3/CD28 beads and IL-2 (Activated).

                Our findings reveal robust TCR detection in both experimental conditions, underscoring the versatility and dependability of our methodology across various T cell states. Whether profiling primary T cells or their activated counterparts, our approach guarantees precise and comprehensive characterization of the TCR repertoire, offering invaluable insights into immune responses and cellular dynamics.

                Rely on our advanced profiling techniques to deliver meticulous and high-fidelity data, facilitating a deeper comprehension of T cell biology and immunological processes. With our innovative methodologies, explore the intricacies of the immune system with confidence and clarity.

                Comprehensive immune repertoire detection

                Experience unparalleled detection of the immune repertoire with the Evercode™ TCR kit, designed to provide the most comprehensive profile available. In a groundbreaking study encompassing 8 donors, our kit identified nearly 500,000 unique beta chain clonotypes.

                Remarkably, the vast majority of these clonotypes were classified as rare, highlighting the sensitivity and depth of our detection capabilities. With the Evercode™ TCR kit, you can uncover the full spectrum of immune diversity, from common to exceedingly rare clonotypes, empowering you to explore the intricacies of immune responses with unprecedented precision and breadth.

                tcr parse workflow

                Ready to Order?

                Our team can help you in placing the order. Click below to get a quote and fast ordering.

                Let’s Find You an Application That Helps
                Your Research

                Get a call from your local Decode Science representative to help you find the best fit genomics products for you.







                  Or give us a call at:

                  1300 581 991