Entries by Harshita Sharma

Saphyr

PRODUCTS

Saphyr

Saphyr System

Reveal genome-wide structural variation with the Saphyr™ optical genome mapping system.

Consistently identify structural variants across all classes with a resolution as low as 500 base pairs (bp) and a variant allele frequency (VAF) as low as 5% utilizing optical genome mapping (OGM) through the Saphyr™ system. Saphyr™ stands as the foremost tool for detecting structural variants, surpassing the capabilities of next-generation sequencing (NGS) methods and traditional cytogenetic approaches, thus capturing genomic variations often overlooked by these technologies.

Achieve broad, unbiased genomic coverage with flexible data collection.

The Saphyr™ system offers adaptable genomic coverage, enabling the identification of heterozygous or infrequent variants present in mosaic samples and heterogeneous tumors.

In just six hours, obtain a comprehensive 100X coverage of a human genome. To uncover deeper and rarer variants, merely prolong the data collection time on Saphyr™ without incurring additional consumable costs. Achieve an impressive 400X coverage within a 24-hour period, facilitating structural variant (SV) detection down to a 5% variant allele frequency (VAF). Extend runtime further to explore variants with even lower VAF levels.

Enjoy seamless integration and workflow efficiency with the Saphyr™ Chip® consumable and Saphyr™ system.

The Saphyr Chips feature hundreds of thousands of highly parallel nanochannels, which efficiently linearize long, labeled DNA molecules, enabling direct imaging of your samples by the Saphyr instrument.

Sample loading onto the Saphyr Chip is swift and straightforward. Easily pipette up to three samples into individual flow cells on the chip. With the capability to load up to two chips onto the Saphyr instrument per run, achieve a maximum throughput of six samples per operation.

Benefit from the Saphyr instrument and chips’ integration of machine learning-based adaptive loading and automatic run optimization. These features ensure hassle-free scanning and optimize throughput speed, allowing for walk-away operation and the fastest achievable throughput for each run.

Guarantee optimal performance through automated health system monitoring accessible remotely.

The Saphyr™ Assure Service offers an optional (opt-in) automated health monitoring feature, which consistently evaluates data quality and instrument functionality. This feature detects potential issues before they impact data quality and performance, enabling Bionano Support to proactively address any concerns and conduct necessary repairs with minimal downtime.

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    Franklin

    PRODUCTS

    Franklin

    Introducing Franklin – a groundbreaking initiative that seamlessly integrates public data sets with real-world evidence, revolutionizing clinical diagnosis, expediting clinical reporting, ensuring consistent classification, all while fostering a thriving community of genomic professionals and upholding data sovereignty and security.

     



    Impacting Lives at the
    Point of Care



    Your Gateway to the
    Actionable Genome



    The Power of
    Community

    Actionable Insights: With Franklin, genomic professionals can redirect their focus from navigating evidence to delving into actionable insights. Our mission is to construct the most extensive and diverse real-world evidence dataset, unlocking answers to any genomic query through the collaborative power of the community, data, and insights.

    Franklin’s Community: Who makes up the Franklin community? Our genomic professionals hail from every facet of the medical genetics domain and span the globe. From genetic counselors, expert physicians, and oncologists to variant scientists, bioinformaticians, clinical geneticists, researchers, and pharmacologists, Franklin unites a diverse array of specialists dedicated to advancing genomic knowledge and practice.

    Franklin dashboard

    Want to try before you buy?

    Our team at Decode Science can help connect you with the experts at Genoox, to arrange a customised demo for your group.

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    Your Research

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      DNBSEQ-E25

      PRODUCTS

      DNBSEQ-E25

      DNBSEQ-E25 : Sequence Your Samples On-The-Go

      Embark on a streamlined sequencing journey from sample to report with the DNBSEQ-E25 sequencer. This compact and standalone system is designed to operate effortlessly inside or outside the lab, providing versatility in its usage. The E25 seamlessly integrates a microfluidic chip, an integrated CMOS detection module, self-luminous dye, and a proprietary computing module. This harmonious combination results in a lightweight and cost-effective instrument that breaks free from location restrictions, allowing you to conduct sequencing processes with ease and efficiency. The DNBSEQ-E25 is your solution for convenient and accessible sequencing wherever you need it.

      Plug-and-Play

      This integrated sequencer is ideal for remote sites, providing ease-of-use and convenience.

      Efficient

      Quick and easy setup means you can start your run in just 10 minutes.

      Hassle-free

      No washing between runs streamlines your sequencing.

      Plug-And-Play

      Experience seamless and hassle-free sequencing with our plug-and-play solution. The DNBSEQ-E25 incorporates an integrated microfluidic sequencing chip with a CMOS detection module underneath each spot. This innovative design minimizes environmental sensitivity, reduces costs, and lightens the weight of the sequencer. The result is a truly plug-and-play system, streamlining the sequencing process and providing you with an efficient and user-friendly solution for your research needs.

      E25 Features with DecodeScience

      Data Analysis Has Never Been Easier

      Simplify your data analysis process with the DNBSEQ-E25, where efficiency meets ease. The advanced model, DNBSEQ-E25A, takes it a step further by incorporating an enhanced computing module capable of running data analysis for various applications, including whole-genome sequencing. These sequencing platforms operate as standalone systems, managing the entire workflow from sample to result without the need for a network connection. This not only ensures ease of use but also eliminates the risk of data breaches, providing you with a secure and reliable solution for your sequencing needs.

      E25 Data

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        DNBSEQ-G400

        PRODUCTS

        DNBSEQ-G400

        MGI G400

        DNBSEQ-G400 : Your Day-to-Day Sequencing Solution

        Elevate your day-to-day sequencing experience with the DNBSEQ-G400, your comprehensive sequencing solution. This system offers a versatile range of sequencing options, accommodating read lengths of up to SE400/PE300 and supporting two flow cell types. With built-in primary data analysis and optimized optical and biochemical systems, the DNBSEQ-G400 ensures a seamless and efficient sequencing process for your daily research needs. Trust in this innovative solution to deliver reliable and high-quality results, making it an essential tool for your routine sequencing endeavors.

        Accurate

        Our proprietary DNBSEQ technology ensures exceptional accuracy, eliminating clonal errors and index hopping-generating >99% SNP/indel precision and sensitivity.

        Versatile

        With a wide dynamic range (between 55 GB and 1440 GB per run per day) the G400 supports multiple read lengths, from SE50 up to SE400 or PE300.

        Flexible

        Choose between two flow cell types, depending on your throughput and runtime requirements. PE150 sequencing can be completed in as little as 37 hours.

        Features

        The sequencing platform offers a broad data output range of 55 Gb to 1440 Gb per run, with PE150(FCS) sequencing achieving full capacity in just 37 hours. It supports various read lengths, including SE50, SE100, SE400, PE100, PE150, PE200, and PE300. The platform’s versatility extends to diverse applications, encompassing basic research, clinical research, forensics, and agriculture, making it suitable for a wide range of scientific and investigative endeavors.

        DNBSEQ-G400

        Performance of G400 with DecodeScience

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          DNBSEQ-T7

          PRODUCTS

          DNBSEQ-T7

          DNBSEQ-T7 : Turbocharge your Sequencing

          Experience a sequencing revolution with the T7, designed to turbocharge efficiency across diverse projects such as whole genome, deep exome, epigenome, transcriptome, single-cell omics, spatial omics, and more. The T7 not only optimizes the entire sequencing process but also achieves extraordinary productivity. With the capability to generate a staggering 20,000 30x whole genomes in just one year, all at an affordable cost of $150 per genome, the T7 sets a new benchmark for high-quality data acquisition at an unparalleled speed. Embrace the future of genomics research with the T7, where efficiency meets affordability without compromising data quality.

          Flexible

          The T7 offers unmatched flexibility with its 4 independent flow cells, empowering you to run them at any time without the need to batch large quantities of samples

          Fast

          Achieve 24/7 production with your large sequencing project by generating 7 Tb data in 24 hours with automatic washes in between runs

          Accessible

          With a cost of $150 per Genome or $1.5/Gb, the T7 opens the doors to accessibility for your groundbreaking sequencing projects

          Say Goodbye to Amplification Errors Associated with PCR

          Bid farewell to amplification errors linked with PCR, as our cutting-edge technologies ensure precise and error-free amplification processes. With our advanced solutions, we prioritize accuracy and reliability, ensuring that your results are free from the concerns associated with amplification errors. Embrace a new era in PCR technology where precision and confidence in your data are paramount.

          T7Inside Workflow

          Independent Flow Cells

          Experience unparalleled flexibility in your sequencing workflows with the inclusion of 4 independent flow cells in our technology. These independent flow cells grant you the freedom to run sequencing processes at any time, eliminating the necessity to batch large quantities of samples. This innovative design empowers you to adapt your sequencing runs to specific requirements, offering enhanced efficiency and customization in your research endeavors.

          T7 Quad Cells

          Performane of T7 with DecodeScience

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            DNBSEQ-G99

            PRODUCTS

            DNBSEQ-G99

            G99 with DecodeScience

            DNBSEQ-G99 : The Ultimate in Sequencing Speed

            Introducing the DNBSEQ-G99, the epitome of sequencing speed and efficiency. This groundbreaking sequencer stands as the fastest ever created, offering unparalleled performance in low- to mid-range throughput, making it an exceptional choice for targeted gene and small genome sequencing research. The G99 features a triangular configuration on the patterned array, achieving a higher density of DNA Nanoballs (DNBs) and consequently yielding an impressive data output of up to 48 gigabytes per run.

            Equipped with a proprietary high-resolution objective lens and a high-precision temperature control system, the DNBSEQ-G99 sets a new standard for efficiency. With a remarkable run time for PE150 sequencing, completing the process within just 12 hours, this sequencer ensures swift and reliable results. Notably, during PE100 or PE150 sequencing runs, informative preliminary reports are available within the first 2.5 hours, providing researchers with rapid insights into their experiments. The DNBSEQ-G99 redefines sequencing capabilities, offering researchers an unprecedented combination of speed, density, and data output for accelerated and informative sequencing workflows.

            Fast

            Get up to 48 Gb (PE150 sequencing) in less than 12 hours.

            Flexible

            Run two independent flow cells at any time.

            Easy-to-Use

            Pre-loaded cartridges minimize human errors.

            Dual Flow Cells for Maximum Flexibility

            The DNBSEQ-G99 introduces a remarkable feature—dual flow cells for maximum flexibility. This innovative capability allows the sequencer to run two flow cells independently, providing users with the adaptable option to plug-and-play as needed. This dual-flow cell design enhances versatility and enables researchers to tailor their sequencing experiments to specific requirements, further expanding the utility and flexibility of the DNBSEQ-G99 in various applications.

            Dual Flow Cells for Maximum Flexibility G99

            Get up to 48 Gb per sequencing run

            Unlock unparalleled sequencing capabilities with the DNBSEQ-G99 and achieve up to 48 gigabytes of data per sequencing run. This impressive data output sets a new standard in sequencing efficiency, providing researchers with extensive genomic information in a single run. The DNBSEQ-G99 empowers users to generate large volumes of high-quality data, enabling comprehensive insights and accelerating advancements in genomics research.

            Performance of G99 with DecodeScience

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              MGISP-7000

              PRODUCTS

              MGISP-7000

              MGISTP-7000 Features with DecodeScience

              MGISP-7000: Precision Meets Speedy Automation

              The MGISTP-7000 ushers in a new era of laboratory automation, meticulously designed to fulfill the requirements of high productivity without compromising safety or quality. This innovative system seamlessly integrates key functionalities, including barcode identification, tube decapping, automated liquid transfer, and negative pressure protection. By doing so, it establishes itself as a comprehensive and efficient sample preparation solution, streamlining processes and ensuring precision throughout the laboratory workflow.

              High Reliability

              Barcode data can be auto-transferred to other automation or LIMS for traceability

              Safe

              Two HEPA filters and UV light enhance safety for liquid transfers and lab technicians

              Automated

              Load sample tubes in a standard rack with one click to automate pre-analysis steps

              High-Throughput Automated Nucleic Acid Extraction Platform

              The MGISTP-7000 stands as a groundbreaking advancement in laboratory automation, specifically revolutionizing sample transfer and nucleic acid detection processes. Noteworthy for its unwavering commitment to safety, the system incorporates dual HEPA filters and an integrated UV light, creating and maintaining a pristine, contamination-free environment. The ISO5 air filter captures an impressive 99.995% of particles at 0.3um, complemented by a specialized venting mechanism efficiently removing potentially contaminated air from the lab space.

              In terms of user experience, the MGISTP-7000’s software is designed with a strong emphasis on user-centricity. With a single click, it automates pre-analytical steps, showcasing both efficiency and user-friendly operation. The robust mechanics of the system can transfer 192 samples to 96-Well Microplates in just 40 minutes, further contributing to its powerful and efficient performance.

              On the connectivity front, the MGISTP-7000 stands out for its compatibility with ZLIMS, allowing for seamless integration with third-party analytical instruments. This adaptability ensures its compatibility with the evolving needs of laboratory workflows.

              Selecting the MGISTP-7000 guarantees a harmonious blend of efficiency, safety, and advanced capabilities in your lab workflows, representing a significant step forward in high-throughput automated nucleic acid extraction platforms.

              About MGISTP-7000 with DecodeScience

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                MGISP-3000

                PRODUCTS

                MGISP-3000

                MGISP-3000 with DecodeScience

                MGISP-3000: Unmatched Speed, Unrivaled Safety

                MGISP-3000 establishes a new benchmark in laboratory automation, harmonizing high-throughput efficiency with unmatched safety measures. Boasting features such as ISO5 air filtration, one-click sample pre-analysis, and seamless ZLIMS integration, it provides a comprehensive and secure solution for modern lab workflows.

                High Reliability

                Barcode data can be auto-transferred to other automation or LIMS for traceability

                Safe

                Two HEPA filters and UV light enhance safety for liquid transfers and lab technicians

                Automated

                Load sample tubes in a standard rack with one click to automate pre-analysis steps

                MGISP-3000: Elevating Lab Automation and Safety Standards

                 

                The MGISP-3000 stands as a pinnacle in lab automation, seamlessly blending high-throughput efficiency with a paramount focus on safety. With features such as ISO5 air filters and external exhaust, it creates an ultra-clean workspace, ensuring a secure environment for various lab tasks.

                Its user-friendly design simplifies operations with a single-click automation of pre-analysis steps, guaranteeing a swift and error-free experience through an intuitive interface. This innovation not only prioritizes safety but also enhances the overall efficiency of laboratory workflows.

                The MGISP-3000 is future-ready, demonstrating seamless integration capabilities with ZLIMS and third-party systems like RT-PCR. This adaptability makes it a versatile solution for evolving lab requirements, ensuring it stays in sync with the latest advancements in the field.

                Moreover, MGISP-3000 goes beyond the conventional by combining top-notch safety measures, streamlined operations, and scalability. It introduces features such as barcode tracking and automated tube sealing, providing a comprehensive solution that meets the demands of high throughput without compromising quality.

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                  MGISP-100

                  PRODUCTS

                  MGISP-100

                  MGISP-100 With DecodeScience

                  MGISP-100 : Precision Prep, Peak Performance

                  Introducing MGISP-100, an advanced automated workstation featuring an 8-channel pipette, specifically designed for sequencing library preparation. This state-of-the-art system excels in processing samples in bulk, guaranteeing both stability and cost-effectiveness to elevate lab productivity. Tailored to meet user requirements, MGISP-100 comes equipped with a range of integrated tools, including PCR machines, UV lamps, and temperature modules. It promotes hands-free, precise, and streamlined operations, ensuring efficient and reliable sequencing library preparation processes.

                  Open Platform

                  Tailored development crafted to meet specific and unique requirements

                  Comprehensive Protection

                  Equipped with a UV lamp and laminar flow hood for a thorough contamination prevention approach

                  Comprehensive Functions

                  Incorporates essential functional modules such as the PCR machine, magnetic rack, temperature modules

                  Economic & Efficient

                  Fully autonomous system, processes samples in bulk, significantly minimising the need for manual intervention

                  The MGISP-100 stands as an advanced automated workstation

                  The MGISP-100 represents a pinnacle in automated workstations, skillfully designed with an 8-channel pipette to facilitate seamless sequencing library preparations. Its batch processing capability ensures uniform outputs, optimizing operational expenses and elevating laboratory efficiency. In addition to its core features, the MGISP-100 is equipped with a suite of integrated tools, including PCR machines, UV lamps, and precise temperature modules, ensuring a meticulous and autonomous operational experience.

                  The versatile capabilities of MGISP-100 extend across various stages of the laboratory workflow, encompassing nucleic acid extraction, enzymatic reactions, size selection, DNB making, magnetic beads purification, PCR, target capture, and incorporating a HEPA system for enhanced contamination control.

                  MGISP-100 Workflow and Features

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                    MGISP-NE32

                    PRODUCTS

                    MGISP-NE32

                    MGI NE32

                    MGISP-NE32 : Precision Extraction, Rapid Results

                    The MGISP-NE32 stands as a cutting-edge extractor, prioritizing both safety and efficiency. Distinguished by features such as an adjustable mixing module and UV pollution control, it establishes itself as a dependable and advanced option for nucleic acid extraction.

                    Efficient

                    Processing magnetic particles and extracting nucleic acid from 16/32 samples in 9 mins

                    Stable

                    Specialized heating block for 96-well plate ensures consistent heating

                    Safe

                    UV lamp and 96-well plate with disposable tip prevent sample cross-contamination

                    Flexible

                    Adjustable mixing module with varied modes; fits multiple magnetic particles and reagents

                    Automated Nucleic Acid Extraction Excellence

                    The MGISP-NE32 stands as a pioneering force in nucleic acid extraction, establishing unprecedented standards. Harnessing advanced magnetic rod technology, it efficiently handles a broad spectrum of samples. The platform’s distinctive adjustable mixing module, combined with the UV lamp and the 96-well pre-packaged plate, ensures unparalleled purity in extractions. Its intuitive interface streamlines program management, and adaptability with various particles and reagents enhances its versatility. The inclusion of a specially crafted heating block guarantees uniform results, solidifying the MGISP-NE32 as the ideal choice for professionals seeking speed, precision, safety, efficiency, versatility, intuitiveness, and consistency in nucleic acid extraction.

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