PRODUCTS

Arrayed gRNA Libraries

Smarter, Faster, and More Efficient CRISPR Screening

Achieve unparalleled knockout efficiency with EditCo’s multi-guide CRISPR design. Our Arrayed CRISPR gRNA Libraries eliminate the inefficiencies of traditional loss-of-function screens, offering a reliable and ready-to-transfect solution. With up to three spatially coordinated sgRNAs per gene, our approach ensures higher knockout success, reduces false negatives, and eliminates the need for complex NGS data analysis. Designed for both human and mouse genes, our libraries provide fast delivery, robust quality control, and seamless Sanger sequencing analysis—so you can focus on results, not troubleshooting.

Whole Genome CRISPR Libraries for Comprehensive Gene Editing

EditCo’s Whole Human and Whole Mouse Genome Libraries provide unmatched gene coverage with our multi-guide design, ensuring high editing efficiency across 20,000+ gene targets. Designed for seamless transfection, these libraries reduce false negatives and eliminate time-consuming preparation, making large-scale CRISPR screening easier than ever.

– Comprehensive Coverage: Target the entire human or mouse genome with high knockout efficiency.
– Ready-to-Use Libraries: Pre-plated and transfection-ready, minimizing preparation time.
– Enhanced Stability: Chemically modified sgRNAs resist degradation and prevent immune responses.
– Flexible Formats: Available in 96- or 384-well plates with multi-guide sgRNAs for reliable gene disruption.

Accelerate Target Discovery with Pathway Libraries

EditCo’s 30+ Pathway Libraries, including druggable targets, GPCRs, kinases, and immuno-oncology genes, provide a powerful tool for target identification studies. Designed with our multi-guide CRISPR strategy, these libraries ensure high knockout efficiency and fewer false negatives. Select libraries ship in as little as one week, helping you start your screen faster.

– Diverse Pathway Coverage: Includes key gene sets for drug discovery and functional studies.
– Fast Shipping: Select libraries ready to ship within a week.
– High-Efficiency Knockouts: Multi-guide sgRNAs deliver precise, predictable gene disruption.
– Ready-to-Use Format: Available in 96- or 384-well plates with modified sgRNAs for stability.

Available Gene Pathways

Optimal Knockout Efficiency for High-Throughput Screening

XDel technology delivers precise, high-efficiency knockouts by using a multi-guide RNA strategy that ensures consistent and reliable gene editing. Unlike traditional single-guide methods, XDel induces fragment deletions in early exons, maximizing on-target accuracy while minimizing variability and off-target effects.

Superior editing efficiency – Multi-guide design achieves higher and more consistent knockouts
Reduced off-target effects – XDel minimizes unintended edits compared to single-guide methods
Sustained knockout effects – Gene edits remain stable across multiple cell passages
High viability & protein depletion – Maintains cell health while ensuring effective functional knockouts

Achieve robust genotype and phenotype screening with XDel’s optimized CRISPR knockout technology.