PRODUCTS
Evercode TCR Mini
Unlock the complexity of the immune repertoire with our innovative solution: single-cell TCR profiling combined with whole transcriptome analysis—all without the need for additional instrumentation.
With our advanced technology, you can achieve sensitive detection of TCRs while simultaneously measuring transcriptome-wide gene expression, including crucial T-cell subtype markers. Dive deep into the cellular landscape and gain unparalleled insights by analyzing paired alpha and beta sequences within the same cell.
This groundbreaking approach empowers you to uncover the intricate interplay between TCR diversity and gene expression profiles at the single-cell level, providing a comprehensive understanding of immune responses and cellular heterogeneity. Say goodbye to the limitations of traditional methods and embark on a new era of immunogenomics research with our integrated solution.
EXPONENTIALLY
SCALABLE
Evercode's combinatorial barcoding
enables you to dramatically
scale up the cells and samples per experiment.
NO INSTRUMENT
REQUIRED
If you have a centrifuge,
thermal cycler,
and some pipettes,
you’re ready to go.
UNMATCHED DATA QUALITY
Better detect lowly expressed
genes and avoid ambient RNA common
in droplet-based
single cell sequencing.
WORKS WITH FIXED CELLS AND NUCLEI
Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.
High TCR detection in activated and primary T cells
Experience high TCR detection in both activated and primary T cells with our advanced profiling techniques. In our study, T cells isolated from peripheral blood mononuclear cells (PBMCs) underwent two distinct conditions: direct profiling (Primary) and activation through culture for 3 days with CD3/CD28 beads and IL-2 (Activated).
Our results demonstrate robust TCR detection in both scenarios, showcasing the versatility and reliability of our methodology across different T cell states. Whether profiling primary T cells or activated counterparts, our approach ensures accurate and comprehensive characterization of the TCR repertoire, providing invaluable insights into immune responses and cellular dynamics.
Count on our advanced profiling techniques to deliver precise and high-quality data, enabling deeper understanding of T cell biology and immunological processes.
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